There will be almost ten billion people living on Earth by 2050 and two billion of them will be over the age of 60. Growing old is the primary risk factor for multiple chronic and life threatening conditions such as diabetes or cardiovascular disease. This burdensome morbidity is the most distressing aspect of old age – compromising individual independence and straining collective healthcare systems.
Making a drug is like trying to pick a lock at the molecular level. There are two ways in which you can proceed. You can try thousands of different keys at random, hopefully finding one that fits. The pharmaceutical industry does this all the time – sometimes screening hundreds of thousands of compounds to see if they interact with a certain enzyme or protein. But unfortunately it’s not always efficient – there are more drug molecule shapes than seconds have passed since the beginning of the universe.
Research into how we can keep our brains healthy as we age has gained momentum in recent years. There is now an increased focus on the changes that we can makes to our health and lifestyle, which may prevent dementia. Here are some things that research has shown reduce a person’s risk of cognitive decline with age.